Centro de Documentação da PJ
Monografia
 CD200 |
Investigations on the use of Samplematrix to stabilize crime scene biological samples for optimized analysis and room temperature storage [Documento electrónico] / Katherine A. Roberts, Donald J. Johnson.- [S.l.] : ed. do a., 2012.- 1 CD-ROM ; 12 cm
Research report submitted to the U.S. Department of Justice Award no. 2007-DN-BX-K172. Ficheiro de 7,86 MB em formato PDF (296 p.). Disponível também em: https://www.ncjrs.gov/pdffiles1/nij/grants/237838.pdf. Acedido a 01 de junho de 2012.
PRESERVAÇÃO DA PROVA, ADN, ANÁLISE DE VESTÍGIOS, BIOLOGIA FORENSE
Storage and preservation of biological evidence are key forensic issues that are currently
under investigation in anticipation of more cost saving and effective stabilization methods. Once
evidence has been identified and collected at a crime scene, it is typically stored for analysis
later. Storing biological evidence at subzero temperatures is one of the current methods
employed to prevent DNA degradation until time of analysis; however, previous studies have
shown that freezing biological evidence does not completely cease the degradation process. In
addition, it has been shown that repeated freezing and thawing of biological evidence may add to
the degradation effects. The research presented here evaluates a proprietary platform technology
for the dry storage of biological materials at ambient temperature. The technology behind this
room temperature stability is primarily adopted from natural principles and is based on the DNA
stabilizing properties of small molecules such as trehalose. Three non-lysis formulations (SM1,
SM2, and SM3) and one lysis formulation were evaluated with approximately 7,500 samples.