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| BUTTON, Jennifer Use of reference materials in toxicology / Jennifer Button In: Forensic toxicology : drug use and misuse / ed. Susannah Davies, Atholl Johnston and David Holt. - Cambridge : The Royal Society of Chemistry, 2016. ISBN 978-1-78262-156-0. p. 370-399. TOXICOLOGIA FORENSE, NORMALIZAÇÃO, OBRA DE REFERÊNCIA Importance of standardisation and harmonisation. The language of metrology. International System of Units. Metrological traceability. Measurement uncertainty. (Certified) reference materials. Quality control materials. Accreditation for reference material producers. Requirements for independent sources. Certificates of analysis. Structural confirmation. Purity. Guidance for selection and use of reference materials. Distinguishing between Chemicals and Reference Materials. Weighing environment. Neat versus Solutions. Free base versus Salts. Recovering reference materials from their container. Dealing with low quantity reference materials. Correct selection of solvent. Stability. Databases for certified reference materials. CCQM. Import and export of controlled drug reference materials. Import and export exemptions. Supplementary reading. References. |